The Science

The Science

Inside the engine:
The science behind
the longevity OS

Inside the engine:
The science behind
the longevity OS

The NU Knowledge graph

Developed over five years by a multidisciplinary team of scientists and doctors, our AI-powered bioinformatics operating system decodes complex biological data to deliver multi-omic health insights, multiple biological age clocks and expert-reviewed, evidence-based recommendations.

The NU Knowledge graph

VO2max

Blood

Wearables

Questionnaires

Body Composition

Age Clocks

17+ Health Insights

Test Deep Dives

Microbiome

Epigenome

Genome

4 Guides

Digital Twin

Integrative analysis of a growing number of biomarkers

Integrative analysis of a growing number of biomarkers

1180+

Key biomarkers

5K+

Nodes

3M+

Relationships

3K+

Peer reviewed references

Engine

A tech stack
built for scale

A fully modular, internally developed engine—built from the ground up with proprietary science and technology.

Raw Data

Raw Data

Raw Data

Genome

Gut microbiome

Blood

Epigenome

Physiome

Wearables

Epigenome

Physiome

Wearables

Bioinformatic entities

Bioinformatic entities

Bioinformatic entities

SNPs, variants

Microbial species, Genera, Metabolic pathways

Blood biomarkers, ratios, optimal ranges

Body composition, VO2 max

Sleep, HRV, Activity, Glucose level

Methylation status of CpGs

Body composition, VO2 max

Sleep, HRV, Activity, Glucose level

Methylation status of CpGs

Science engine

Science engine

Science engine

Methylation pathways, PGS scores

Multiomic Age Clocks

Multiomic Risk profiles

Nutrition plans and food rankings

Personalised supplement formulas

Specialised exercise programs

Methylation pathways, PGS scores

Multiomic Age Clocks

Multiomic Risk profiles

Deep Dives

Deep Dives

Deep Dives

In-depth analysis across hundreds of gene variants, genetic traits, microbial species, metabolic pathways, 60+ blood biomarkers, body composition metrics, VO2 max and 10 key epigenetic ageing factors.

In-depth analysis across hundreds of gene variants, genetic traits, microbial species, metabolic pathways, 60+ blood biomarkers, body composition metrics, VO2 max and 10 key epigenetic ageing factors.

In-depth analysis across hundreds of gene variants, genetic traits, microbial species, metabolic pathways, 60+ blood biomarkers, body composition metrics, VO2 max and 10 key epigenetic ageing factors.

Age Clocks

Age Clocks

Age Clocks

A comprehensive view of biological ageing using multiple validated clocks, including Blood Age, Microbiome Age, and Epigenetic Age.

A comprehensive view of biological ageing using multiple validated clocks, including Blood Age, Microbiome Age, and Epigenetic Age.

A comprehensive view of biological ageing using multiple validated clocks, including Blood Age, Microbiome Age, and Epigenetic Age.

Health Insights

Health Insights

Health Insights

Summaries of 17+ key biological processes, integrating all available data to pinpoint critical health drivers and prioritise the most impactful areas for intervention.

Summaries of 17+ key biological processes, integrating all available data to pinpoint critical health drivers and prioritise the most impactful areas for intervention.

Summaries of 17+ key biological processes, integrating all available data to pinpoint critical health drivers and prioritise the most impactful areas for intervention.

Guides

Guides

Guides

Expert-reviewed recommendations across Food, Exercise, Lifestyle, and Supplements. Deeply personalised, evidence-based, and aligned with individual health insights and goals.

Expert-reviewed recommendations across Food, Exercise, Lifestyle, and Supplements. Deeply personalised, evidence-based, and aligned with individual health insights and goals.

Expert-reviewed recommendations across Food, Exercise, Lifestyle, and Supplements. Deeply personalised, evidence-based, and aligned with individual health insights and goals.

Science

Company

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Science

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